![]() ![]() At present, breast cancer is one of the most frequently diagnosed malignancies worldwide, accounting for 23% of female cancer diagnoses, as well as a leading cause of cancer-related mortality in women, responsible for 14% of cancer deaths. Estrogen receptor positivity ( P < 0.001), progesterone receptor positivity ( P = 0.010), invasive lobular carcinoma ( P = 0.009) and receiving endocrine therapy ( P = 0.001) predicted longer TTR.īreast cancer is a heterogenous disease, with varying molecular properties, multimodal therapeutic strategies and expected prognoses. Two hundred sixty-five consecutive patients who developed breast cancer recurrence were included median age at metastasis was 59.3 years (range 27–87 years), and median time to recurrence (TTR) was 47.7 ± 38.5 months (range 3.0–194.3 months).
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